Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPS8Epidermal growth factor receptor pathway substrate 8. (817 aa)    
Predicted Functional Partners:
ABI1
Abl interactor 1.
    
 
 0.990
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 
 0.988
ENSVPAP00000010337
annotation not available
    
 
 0.981
CASK
Calcium/calmodulin dependent serine protein kinase.
   
 0.948
MYO3A
Myosin IIIA.
    
 0.898
BAIAP2L1
BAR/IMD domain containing adaptor protein 2 like 1.
   
 
 0.893
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 
 0.885
ZNF644
Zinc finger protein 644.
    
 
 0.854
MYO10
Myosin X.
    
 0.847
CBL
Cbl proto-oncogene.
    
   0.831
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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