Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1570 aa)    
Predicted Functional Partners:
MAP2K6
Mitogen-activated protein kinase kinase 6.
    
 
 0.933
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 
 0.910
MAPK14
Mitogen-activated protein kinase 14.
    
 
 0.880
MAP2K1
Mitogen-activated protein kinase kinase 1.
    
 
 0.879
MAP2K5
Mitogen-activated protein kinase kinase 5.
    
 
 0.879
ENSVPAP00000006432
annotation not available
    
 
 0.874
MAPK7
Mitogen-activated protein kinase 7.
    
 
 0.825
MAP2K4
Mitogen-activated protein kinase kinase 4.
    
 
 0.811
ASB3
Ankyrin repeat and SOCS box containing 3.
    
 
 0.695
CD2AP
CD2 associated protein.
    
   0.689
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
Server load: medium (44%) [HD]