Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXW7F-box and WD repeat domain containing 7. (618 aa)    
Predicted Functional Partners:
CUL1
Cullin 1.
    
 0.994
SKP1
S-phase kinase associated protein 1.
    
 0.994
RBX1
Ring-box 1.
    
 0.992
CCNE1
Cyclin E1.
    
 0.989
ENSVPAP00000005509
annotation not available
    
 0.989
RICTOR
RPTOR independent companion of MTOR complex 2.
    
 
 0.988
MYC
MYC proto-oncogene, bHLH transcription factor.
    
 
 0.988
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.984
ENSVPAP00000007182
annotation not available
    
 0.977
ENSVPAP00000011282
annotation not available
    
 
 0.972
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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