Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP2K6Mitogen-activated protein kinase kinase 6. (334 aa)    
Predicted Functional Partners:
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
0.999
MAPK14
Mitogen-activated protein kinase 14.
  
0.999
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
  
 
0.997
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
     
 0.982
MAPK9
Mitogen-activated protein kinase 9.
  
 
0.974
MAPK8
Mitogen-activated protein kinase 8.
  
 
0.968
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
     
 0.963
TAOK1
TAO kinase 1.
  
 
0.961
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
  
 
 
0.960
RIPK1
Receptor interacting serine/threonine kinase 1.
    
0.953
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.