Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKRAProtein activator of interferon induced protein kinase EIF2AK2. (290 aa)    
Predicted Functional Partners:
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
    
 0.999
DICER1
Dicer 1, ribonuclease III.
    
 0.996
ENSVPAP00000003854
annotation not available
    
 
 0.969
STAU1
Staufen double-stranded RNA binding protein 1.
    
 
 0.967
AGO4
Argonaute RISC component 4.
    
 0.958
AGO1
Argonaute RISC component 1.
    
 0.958
AGO3
Argonaute RISC catalytic component 3.
    
 0.958
ENSVPAP00000010722
annotation not available
    
 0.904
STRBP
Spermatid perinuclear RNA binding protein.
    
 
 0.890
STAU2
Staufen double-stranded RNA binding protein 2.
    
 
 0.881
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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