Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXW8F-box and WD repeat domain containing 8. (551 aa)    
Predicted Functional Partners:
RBX1
Ring-box 1.
    
 0.999
SKP1
S-phase kinase associated protein 1.
    
 0.998
CUL1
Cullin 1.
    
 0.992
CUL3
Cullin 3.
    
 0.875
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
   
 0.826
UBA3
Ubiquitin like modifier activating enzyme 3.
   
 0.764
FBXO4
F-box protein 4.
    
 0.764
KCTD3
Potassium channel tetramerization domain containing 3.
     
 0.706
SKP2
S-phase kinase associated protein 2.
    
 0.703
COQ9
Coenzyme Q9.
    
 0.702
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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