Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MELKMaternal embryonic leucine zipper kinase. (650 aa)    
Predicted Functional Partners:
PBK
PDZ binding kinase.
   
 0.972
DLGAP5
DLG associated protein 5.
   
  
 0.967
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.963
ENSVPAP00000009570
annotation not available
   
  
 0.957
NCAPG
non-SMC condensin I complex subunit G.
   
  
 0.952
CDK1
Cyclin dependent kinase 1.
   
 
 0.948
KIF20A
Kinesin family member 20A.
   
 
 0.945
TTK
TTK protein kinase.
   
  
 0.943
KIF4A
Kinesin family member 4A.
   
 
 0.942
KIF11
Kinesin family member 11.
   
  
 0.938
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
Server load: low (20%) [HD]