STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROBO1Roundabout guidance receptor 1. (1655 aa)    
Predicted Functional Partners:
SLIT2
Slit guidance ligand 2.
   
 0.998
SLIT3
Slit guidance ligand 3.
   
 0.967
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1.
    
 0.948
PAK5
P21 (RAC1) activated kinase 5.
   
 0.937
PAK3
P21 (RAC1) activated kinase 3.
   
 0.932
PAK2
P21 (RAC1) activated kinase 2.
   
 0.932
USP33
Ubiquitin specific peptidase 33.
    
 0.902
NYX
Nyctalopin.
   
 0.863
GDNF
Glial cell derived neurotrophic factor.
     
 0.788
ENSVPAP00000006080
annotation not available
   
 0.728
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.