Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APPAmyloid beta precursor protein. (749 aa)    
Predicted Functional Partners:
NAE1
NEDD8 activating enzyme E1 subunit 1.
    
 0.987
ENSVPAP00000005661
annotation not available
    
 0.978
ENSVPAP00000001355
annotation not available
   
 0.964
SNCA
Synuclein alpha.
    
 0.955
ENSVPAP00000010010
annotation not available
   
 0.954
NCSTN
Nicastrin.
    
 0.936
ENSVPAP00000008126
annotation not available
   
 
 0.933
MAP2
Microtubule associated protein 2.
    
 
 0.921
TTR
Transthyretin.
    
 0.911
CRYAB
Crystallin alpha B.
   
 
 0.891
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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