Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NAIPNLR family apoptosis inhibitory protein. (971 aa)    
Predicted Functional Partners:
NLRC4
NLR family CARD domain containing 4.
  
 
0.980
CASP9
Caspase 9.
   
 0.968
XIAP
X-linked inhibitor of apoptosis.
   
 0.962
ENSVPAP00000010662
annotation not available
    
 0.940
CASP3
Caspase 3.
   
 0.934
APAF1
Apoptotic peptidase activating factor 1.
   
 0.868
ROCK1
Rho associated coiled-coil containing protein kinase 1.
    
 0.864
ENSVPAP00000005090
annotation not available
   
 0.856
ENSVPAP00000008658
annotation not available
   
 0.855
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.839
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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