Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESF1ESF1 nucleolar pre-rRNA processing protein homolog. (845 aa)    
Predicted Functional Partners:
NOL10
Nucleolar protein 10.
   
 
 0.994
DDX10
DEAD-box helicase 10.
   
 
 0.994
UTP6
UTP6 small subunit processome component.
   
 
 0.990
MPHOSPH10
M-phase phosphoprotein 10.
   
 
 0.989
KRR1
KRR1 small subunit processome component homolog.
   
 
 0.989
AATF
Apoptosis antagonizing transcription factor.
   
 
 0.988
UTP18
UTP18 small subunit processome component.
   
 
 0.987
WDR36
WD repeat domain 36.
   
 
 0.986
BYSL
Bystin like.
   
 
 0.983
UTP4
UTP4 small subunit processome component.
   
 
 0.980
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
Server load: medium (46%) [HD]