Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABCC8ATP binding cassette subfamily C member 8. (1168 aa)    
Predicted Functional Partners:
KCNJ8
Potassium inwardly rectifying channel subfamily J member 8.
   
 0.997
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.992
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
   
 0.880
ABCC9
ATP binding cassette subfamily C member 9.
   
 
 0.858
SLC30A8
Solute carrier family 30 member 8.
     
 0.816
PCSK2
Proprotein convertase subtilisin/kexin type 2.
  
 
 0.761
PCSK1
Proprotein convertase subtilisin/kexin type 1.
   
 
 0.754
KCNJ6
Potassium inwardly rectifying channel subfamily J member 6.
   
 0.748
KCNJ3
Potassium inwardly rectifying channel subfamily J member 3.
    
 0.702
PAX4
Paired box 4.
      
 0.688
Your Current Organism:
Vicugna pacos
NCBI taxonomy Id: 30538
Other names: Lama guanicoe pacos, Lama pacos, V. pacos, alpaca
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