STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
97782pPredicted protein. (204 aa)    
Predicted Functional Partners:
A0A2K3DDC1
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 0.999
A0A2K3E6K5
Sld5 domain-containing protein.
   
 0.999
A8J7C1_CHLRE
Predicted protein.
   
 0.999
CDC45
Cell division cycle protein 45.
   
 0.994
MCM5
DNA helicase; Belongs to the MCM family.
   
 0.989
A0A2K3DIP5
DNA helicase; Belongs to the MCM family.
   
 0.988
MCM3
DNA helicase; Belongs to the MCM family.
   
 0.986
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.984
A0A2K3CSZ2
Uncharacterized protein.
   
 
 0.979
A0A2K3D9E2
DNA_pol_E_B domain-containing protein.
   
 
 0.954
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, SAG 53.72 [[Chlamydomonas smithii]], SAG 54.72 [[Chlamydomonas smithii]], UTEX 90
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