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FEN1 protein (Chlamydomonas reinhardtii) - STRING interaction network
"FEN1" - Nuclease, Rad2 family in Chlamydomonas reinhardtii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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FEN1Nuclease, Rad2 family; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as [...] (396 aa)    
Predicted Functional Partners:
PCN1
PCNA proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (268 aa)
     
  0.997
EDO95996
MSH2-like protein (221 aa)
   
  0.989
EDO99592
Predicted protein (1384 aa)
     
  0.976
RFC4
DNA replication factor C complex subunit 4 (332 aa)
   
  0.975
EDP01005
Predicted protein (594 aa)
   
  0.973
LIG1
DNA ligase (813 aa)
   
  0.971
MCM5
Minichromosome maintenance protein 5 (718 aa)
     
 
  0.969
MRE11
MRE11 eukaryotic DNA repair protein (163 aa)
   
  0.967
RFC3
DNA replication factor C complex subunit 3 (356 aa)
   
  0.961
MLH1
Mismatch repair protein (1007 aa)
   
  0.958
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonadaceae, Chlamydomonadales, Chlamydomonas, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, Chlorophyceae, Volvocales, Volvocida
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