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FAP59 protein (Chlamydomonas reinhardtii) - STRING interaction network
"FAP59" - Flagellar associated protein in Chlamydomonas reinhardtii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FAP59Flagellar associated protein; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, by acting as a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (PubMed-25395538). Together with CCDC40/FAP172 forms a 96-nm-long complex in flagella. This complex does not act as a physical ruler, but rather act as a negative regulator for radial spokes- the complex lays along specific protofilaments, masking radial spoke binding sites and allowin [...] (894 aa)    
Predicted Functional Partners:
FAP250
Flagellar associated protein; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex (412 aa)
     
   
  0.940
FAP119
Flagellar associated protein (306 aa)
     
   
  0.856
PF2
Component of dynein regulatory complex (471 aa)
     
   
  0.841
EDO99707
Tektin, flagellar protein associated with inner arm dynein; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in flagella and cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (482 aa)
     
   
  0.827
RIB72
Protofilament ribbon protein of flagellar microtubules (635 aa)
     
   
  0.817
CPC1
Protein associated with central pair microtubule complex (1929 aa)
     
   
  0.810
PF9
Flagellar inner arm dynein 1 heavy chain alpha (4625 aa)
     
   
  0.799
IFT81
Intraflagellar transport protein 81; Component of the intraflagellar transport (IFT) complex B- together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis (683 aa)
     
   
  0.797
FAP252
Flagellar associated protein (352 aa)
     
   
  0.787
DRC3
Flagellar associated protein; Key component of the nexin-dynein regulatory complex (N- DRC). Requires for normal flagellar waveform (524 aa)
     
   
  0.785
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonadaceae, Chlamydomonadales, Chlamydomonas, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, Chlorophyceae, Volvocales, Volvocida
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