node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GV64_05115 | GV64_16845 | GV64_05115 | GV64_16845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.846 |
GV64_05115 | GV64_17585 | GV64_05115 | GV64_17585 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.477 |
GV64_05115 | GV64_20245 | GV64_05115 | GV64_20245 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
GV64_05115 | GV64_23975 | GV64_05115 | GV64_23975 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.946 |
GV64_05115 | gcvP | GV64_05115 | GV64_16550 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.918 |
GV64_05115 | gltA | GV64_05115 | GV64_17610 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.906 |
GV64_05115 | gltB | GV64_05115 | GV64_08255 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.888 |
GV64_06935 | GV64_16845 | GV64_06935 | GV64_16845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
GV64_16845 | GV64_05115 | GV64_16845 | GV64_05115 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.846 |
GV64_16845 | GV64_06935 | GV64_16845 | GV64_06935 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
GV64_16845 | GV64_17585 | GV64_16845 | GV64_17585 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.821 |
GV64_16845 | GV64_17675 | GV64_16845 | GV64_17675 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.806 |
GV64_16845 | GV64_20245 | GV64_16845 | GV64_20245 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.821 |
GV64_16845 | GV64_22745 | GV64_16845 | GV64_22745 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.876 |
GV64_16845 | GV64_23975 | GV64_16845 | GV64_23975 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.808 |
GV64_16845 | gcvP | GV64_16845 | GV64_16550 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.865 |
GV64_16845 | gltA | GV64_16845 | GV64_17610 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.811 |
GV64_16845 | gltB | GV64_16845 | GV64_08255 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.876 |
GV64_17585 | GV64_05115 | GV64_17585 | GV64_05115 | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.477 |
GV64_17585 | GV64_16845 | GV64_17585 | GV64_16845 | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.821 |