STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPTNOptineurin. (593 aa)    
Predicted Functional Partners:
ENSMICP00000028639
annotation not available
    
 0.965
ENSMICP00000030592
annotation not available
    
 0.965
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.965
TBK1
TANK binding kinase 1.
    
 0.935
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.905
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.871
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
     
 0.866
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
     
 0.866
IRAK4
annotation not available
    
 0.861
MAP3K20
Mitogen-activated protein kinase kinase kinase 20.
    
 0.857
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.