STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RALGPS2Ral GEF with PH domain and SH3 binding motif 2. (583 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.959
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
    
 0.850
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 0.846
GRAPL
GRB2 related adaptor protein like.
   
 0.811
GRAP2
GRB2 related adaptor protein 2.
   
 0.806
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.760
PTPN11
annotation not available
    
 0.760
ENSMICP00000043424
annotation not available
    
 0.760
MET
Hepatocyte growth factor receptor.
    
 0.758
MST1R
Macrophage stimulating 1 receptor.
    
 0.758
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.