STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (795 aa)    
Predicted Functional Partners:
TNF
Tumor necrosis factor.
    
 0.961
TRADD
TNFRSF1A associated via death domain.
    
 0.958
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.950
LTA
Lymphotoxin alpha.
    
 0.940
FADD
Fas associated via death domain.
   
 0.901
TNFAIP3
TNF alpha induced protein 3.
    
 0.894
CYLD
CYLD lysine 63 deubiquitinase.
    
 0.892
RNF31
annotation not available
    
 0.891
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.890
RBCK1
RANBP2-type and C3HC4-type zinc finger containing 1.
    
 0.881
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.