STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK1P21 (RAC1) activated kinase 1. (544 aa)    
Predicted Functional Partners:
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.991
CDC42
Cell division cycle 42.
   
 0.987
ENSMICP00000020321
annotation not available
   
 0.987
ENSMICP00000036602
annotation not available
   
 0.987
NCK2
NCK adaptor protein 2.
    
 0.985
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.984
ENSMICP00000001997
annotation not available
    
 0.973
NCK1
NCK adaptor protein 1.
    
 0.973
ITSN2
Intersectin 2.
    
 0.969
RAC3
Rac family small GTPase 3.
    
 0.964
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.