STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDEInsulin degrading enzyme. (1004 aa)    
Predicted Functional Partners:
INS
Insulin.
    
 0.988
APP
Amyloid beta precursor protein.
    
 
 0.972
ENSMICP00000006531
annotation not available
    
  0.966
IAPP
Islet amyloid polypeptide.
    
 
 0.966
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.959
GCG
Glucagon.
    
 
 0.950
ENSMICP00000050267
annotation not available
    
  0.939
IGF2
Insulin like growth factor 2.
    
 
 0.938
ENSMICP00000027681
annotation not available
    
 0.930
RPS27A
annotation not available
    
 0.930
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.