STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BACE2Beta-secretase 2. (514 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.923
RTN3
Reticulon 3.
   
 0.919
FYN
FYN proto-oncogene, Src family tyrosine kinase.
   
 
 0.918
RTN4
Reticulon 4.
   
 0.911
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.848
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 0.848
BACE1
Beta-secretase 1.
  
  
0.837
RTN2
Reticulon 2.
   
 0.785
RTN1
Reticulon 1.
   
 0.777
SRMS
Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites.
   
 
 0.773
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.