STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB4Erb-b2 receptor tyrosine kinase 4. (1312 aa)    
Predicted Functional Partners:
NRG1
Neuregulin 1.
    
 0.996
ERBB2
Erb-b2 receptor tyrosine kinase 2.
  
 
0.992
GRB2
Growth factor receptor bound protein 2.
    
 0.990
EGFR
Epidermal growth factor receptor.
  
 
0.989
SHC1
SHC adaptor protein 1.
    
 0.987
NRG2
Neuregulin 2.
    
 0.982
TGFA
Transforming growth factor alpha.
    
 0.980
EREG
Epiregulin.
    
 0.979
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.974
DLG4
Discs large MAGUK scaffold protein 4.
    
 0.970
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.