STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPA1OPA1 mitochondrial dynamin like GTPase. (1015 aa)    
Predicted Functional Partners:
PINK1
PTEN induced kinase 1.
    
 0.958
GAK
Cyclin G associated kinase.
   
 0.952
PRKN
Parkin RBR E3 ubiquitin protein ligase.
    
 0.947
ITSN2
Intersectin 2.
    
 
 0.944
OMA1
OMA1 zinc metallopeptidase.
    
 0.903
ITSN1
Intersectin 1.
    
 
 0.898
MIEF2
Mitochondrial elongation factor 2.
    
 
 0.776
FIS1
Fission, mitochondrial 1.
    
 0.772
PGAM5
PGAM family member 5, mitochondrial serine/threonine protein phosphatase.
    
 0.769
CLDN15
Claudin 15.
    
 0.740
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.