STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNK2Tyrosine kinase non receptor 2. (1088 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 
 0.945
ENSMICP00000020321
annotation not available
    
 
 0.945
ENSMICP00000036602
annotation not available
    
 
 0.945
GRB2
Growth factor receptor bound protein 2.
    
 
 0.919
EGFR
Epidermal growth factor receptor.
    
 
0.882
CLTC
Clathrin heavy chain.
    
 
 0.843
DKKL1
Dickkopf like acrosomal protein 1.
   
    0.792
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
    
 
0.760
SH3RF3
SH3 domain containing ring finger 3.
    
 
 0.670
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.631
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.