NUDT4 protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

NUDT4

Nudix hydrolase domain-containing protein. (181 aa)

Predicted Functional Partners:

ASMTL

0.832

NME8

0.831

H0WY93_OTOGA

0.806

H0XDF7_OTOGA

0.806

EDC4

0.687

XRN1

0.675

NUDT12

0.658

LSM1

0.654

ITPA

0.651

EDC3

0.632

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASMTL	H0WY93_OTOGA	ENSOGAP00000008372	ENSOGAP00000007465	Acetylserotonin O-methyltransferase like.	Uncharacterized protein.	0.873
ASMTL	H0XDF7_OTOGA	ENSOGAP00000008372	ENSOGAP00000013900	Acetylserotonin O-methyltransferase like.	Uncharacterized protein.	0.873
ASMTL	ITPA	ENSOGAP00000008372	ENSOGAP00000001692	Acetylserotonin O-methyltransferase like.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.469
ASMTL	NME8	ENSOGAP00000008372	ENSOGAP00000005072	Acetylserotonin O-methyltransferase like.	NME/NM23 family member 8.	0.828
ASMTL	NUDT4	ENSOGAP00000008372	ENSOGAP00000000088	Acetylserotonin O-methyltransferase like.	Nudix hydrolase domain-containing protein.	0.832
EDC3	EDC4	ENSOGAP00000012943	ENSOGAP00000013954	Enhancer of mRNA decapping 3.	Enhancer of mRNA decapping 4.	0.999
EDC3	LSM1	ENSOGAP00000012943	ENSOGAP00000013575	Enhancer of mRNA decapping 3.	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.	0.952
EDC3	NUDT4	ENSOGAP00000012943	ENSOGAP00000000088	Enhancer of mRNA decapping 3.	Nudix hydrolase domain-containing protein.	0.632
EDC3	XRN1	ENSOGAP00000012943	ENSOGAP00000000151	Enhancer of mRNA decapping 3.	5'-3' exoribonuclease 1.	0.981
EDC4	EDC3	ENSOGAP00000013954	ENSOGAP00000012943	Enhancer of mRNA decapping 4.	Enhancer of mRNA decapping 3.	0.999
EDC4	LSM1	ENSOGAP00000013954	ENSOGAP00000013575	Enhancer of mRNA decapping 4.	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.	0.834
EDC4	NUDT4	ENSOGAP00000013954	ENSOGAP00000000088	Enhancer of mRNA decapping 4.	Nudix hydrolase domain-containing protein.	0.687
EDC4	XRN1	ENSOGAP00000013954	ENSOGAP00000000151	Enhancer of mRNA decapping 4.	5'-3' exoribonuclease 1.	0.991
H0WY93_OTOGA	ASMTL	ENSOGAP00000007465	ENSOGAP00000008372	Uncharacterized protein.	Acetylserotonin O-methyltransferase like.	0.873
H0WY93_OTOGA	H0XDF7_OTOGA	ENSOGAP00000007465	ENSOGAP00000013900	Uncharacterized protein.	Uncharacterized protein.	0.996
H0WY93_OTOGA	ITPA	ENSOGAP00000007465	ENSOGAP00000001692	Uncharacterized protein.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.915
H0WY93_OTOGA	NME8	ENSOGAP00000007465	ENSOGAP00000005072	Uncharacterized protein.	NME/NM23 family member 8.	0.945
H0WY93_OTOGA	NUDT4	ENSOGAP00000007465	ENSOGAP00000000088	Uncharacterized protein.	Nudix hydrolase domain-containing protein.	0.806
H0XDF7_OTOGA	ASMTL	ENSOGAP00000013900	ENSOGAP00000008372	Uncharacterized protein.	Acetylserotonin O-methyltransferase like.	0.873
H0XDF7_OTOGA	H0WY93_OTOGA	ENSOGAP00000013900	ENSOGAP00000007465	Uncharacterized protein.	Uncharacterized protein.	0.996