Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa)    
Predicted Functional Partners:
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.992
VCL
Vinculin.
    
 0.991
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.989
GIT1
GIT ArfGAP 1.
    
 0.988
PARVA
Parvin alpha.
    
 0.988
CRK
CRK proto-oncogene, adaptor protein.
    
 0.988
ILK
Integrin linked kinase.
   
 0.986
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.986
SRC
Tyrosine-protein kinase.
    
 0.983
GIT2
GIT ArfGAP 2.
    
 0.981
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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