Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (631 aa)    
Predicted Functional Partners:
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.994
DELE1
DAP3 binding cell death enhancer 1.
    
 0.988
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
  
 
0.905
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4.
   
 0.902
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
   
 
 0.894
H0WWX1_OTOGA
Tr-type G domain-containing protein.
   
 0.887
H0XQS1_OTOGA
Tr-type G domain-containing protein.
   
 0.887
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
    
   0.885
EIF2B1
Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 
 0.877
EIF2A
Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
   
 
 0.872
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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