Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF135Ring finger protein 135. (448 aa)    
Predicted Functional Partners:
DDX58
DExD/H-box helicase 58.
   
 0.995
H0XMK6_OTOGA
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.962
H0XKZ7_OTOGA
Uncharacterized protein.
    
   0.899
ASPM
Abnormal spindle-like microcephaly-associated protein.
    
   0.899
DHX58
DExH-box helicase 58.
   
 0.896
MAVS
Mitochondrial antiviral signaling protein.
    
 0.833
IFIH1
Interferon induced with helicase C domain 1.
   
 0.832
CTNNAL1
Catenin alpha like 1.
    
   0.787
SQSTM1
Sequestosome 1.
    
 0.735
ZC3HAV1
Zinc finger CCCH-type containing, antiviral 1.
   
 0.730
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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