Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIGGPhosphatidylinositol glycan anchor biosynthesis class G. (982 aa)    
Predicted Functional Partners:
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
    
 0.996
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.985
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
   
 0.971
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
    
 0.953
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
    
 0.938
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
   
 0.914
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
   
 0.913
GANAB
Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.
   
 0.903
TMED10
Transmembrane p24 trafficking protein 10.
    
 
 0.892
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.865
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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