Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H0WI92_OTOGARod_C domain-containing protein. (1134 aa)    
Predicted Functional Partners:
ZW10
Zw10 kinetochore protein.
   
 0.999
ZWILCH
Zwilch kinetochore protein.
   
 0.999
ZWINT
ZW10 interacting kinetochore protein.
   
 
 0.965
BUB1B
Uncharacterized protein.
   
 
 0.941
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.893
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.871
NDC80
NDC80 kinetochore complex component.
   
 
 0.855
H0XKZ7_OTOGA
Uncharacterized protein.
   
 
 0.842
ASPM
Abnormal spindle-like microcephaly-associated protein.
   
 
 0.842
SMC2
Structural maintenance of chromosomes protein.
   
 
  0.824
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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