Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEA1Early endosome antigen 1. (1411 aa)    
Predicted Functional Partners:
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.917
RAB5A
RAB5A, member RAS oncogene family.
    
 0.909
RAB5B
RAB5B, member RAS oncogene family.
    
 0.909
RAB5C
RAB5C, member RAS oncogene family.
    
 0.909
RAB17
RAB17, member RAS oncogene family.
    
 0.903
LAMP1
Lysosomal associated membrane protein 1.
      
 0.887
CD63
Tetraspanin.
      
 0.886
LAMP2
Lysosomal associated membrane protein 2.
      
 0.885
TFRC
Transferrin receptor.
      
 0.884
CANX
Calnexin.
    
 
 0.883
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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