Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL4BCullin 4B; Belongs to the cullin family. (889 aa)    
Predicted Functional Partners:
CUL4A
Cullin 4A isoform 1 (Predicted); Belongs to the cullin family.
  
0.999
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.998
DDB1
Damage specific DNA binding protein 1.
   
 0.998
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.994
DDB2
Damage specific DNA binding protein 2.
    
 0.994
RBX1
Ring-box 1.
    
 0.994
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.993
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.993
DDA1
DET1 and DDB1 associated 1.
    
 0.990
DCAF8
DDB1 and CUL4 associated factor 8.
   
 0.990
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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