Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASTLMetalloendopeptidase. (426 aa)    
Predicted Functional Partners:
PRCP
Prolylcarboxypeptidase.
     
 0.783
DPP7
Dipeptidyl peptidase 7.
     
 0.778
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
    
 
 0.760
APBA1
Amyloid beta precursor protein binding family A member 1.
      
 0.760
SCN1B
Sodium voltage-gated channel beta subunit 1.
      
 0.752
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
   
 
 0.735
XPNPEP1
X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.
   
 
 0.735
ACE
Angiotensin-converting enzyme.
   
 
 0.734
LOC100945027
Angiotensin-converting enzyme.
   
 
 0.734
MME
Membrane metalloendopeptidase.
     
 0.713
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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