Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PROX2Prospero homeobox 2. (592 aa)    
Predicted Functional Partners:
IFT80
Intraflagellar transport 80.
      
 0.850
CATSPER1
Cation channel sperm associated 1.
      
 0.831
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
   0.747
H0WYD2_OTOGA
Uncharacterized protein.
      
 0.677
ZFYVE26
Zinc finger FYVE-type containing 26.
      
 0.666
VRTN
Vertebrae development associated.
      
 0.656
HUS1
Checkpoint protein; Belongs to the HUS1 family.
    
   0.611
HUS1B
Checkpoint protein; Belongs to the HUS1 family.
    
   0.611
FLRT2
Fibronectin leucine rich transmembrane protein 2.
      
 0.585
RIF1
Replication timing regulatory factor 1.
    
   0.576
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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