Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HVCN1Hydrogen voltage gated channel 1. (266 aa)    
Predicted Functional Partners:
LAPTM4A
Lysosomal protein transmembrane 4 alpha.
      
 0.596
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.577
GPN3
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
      
 0.556
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.538
H0X5T5_OTOGA
Ig-like domain-containing protein.
      
 0.532
H0X789_OTOGA
Uncharacterized protein.
     
 0.531
CTNNA1
Catenin alpha 1.
      
 0.507
TCTN1
Tectonic family member 1.
   
  
 0.498
KCNU1
Potassium calcium-activated channel subfamily U member 1.
      
 0.487
FIBIN
Fin bud initiation factor homolog.
      
 0.471
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.