UBE2I protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

UBE2I

Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (137 aa)

Predicted Functional Partners:

RANGAP1

0.999

UBA2

0.999

RANBP2

0.999

H0Y0J5_OTOGA

0.999

ZNF451

0.997

H0XQT3_OTOGA

0.990

SUMO3

0.986

SUMO1

0.986

SAE1

0.985

PIAS1

0.977

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H0XQT3_OTOGA	H0Y0J5_OTOGA	ENSOGAP00000018475	ENSOGAP00000021888	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.916
H0XQT3_OTOGA	PIAS1	ENSOGAP00000018475	ENSOGAP00000012663	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 1.	0.911
H0XQT3_OTOGA	RANBP2	ENSOGAP00000018475	ENSOGAP00000020128	Small ubiquitin-related modifier.	RAN binding protein 2.	0.988
H0XQT3_OTOGA	RANGAP1	ENSOGAP00000018475	ENSOGAP00000007913	Small ubiquitin-related modifier.	Ran GTPase activating protein 1.	0.973
H0XQT3_OTOGA	SAE1	ENSOGAP00000018475	ENSOGAP00000021461	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.978
H0XQT3_OTOGA	SUMO1	ENSOGAP00000018475	ENSOGAP00000019503	Small ubiquitin-related modifier.	Ubiquitin-like domain-containing protein.	0.816
H0XQT3_OTOGA	UBA2	ENSOGAP00000018475	ENSOGAP00000007933	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.976
H0XQT3_OTOGA	UBE2I	ENSOGAP00000018475	ENSOGAP00000001269	Small ubiquitin-related modifier.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.990
H0XQT3_OTOGA	ZNF451	ENSOGAP00000018475	ENSOGAP00000000607	Small ubiquitin-related modifier.	Zinc finger protein 451.	0.914
H0Y0J5_OTOGA	H0XQT3_OTOGA	ENSOGAP00000021888	ENSOGAP00000018475	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.916
H0Y0J5_OTOGA	PIAS1	ENSOGAP00000021888	ENSOGAP00000012663	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 1.	0.953
H0Y0J5_OTOGA	RANBP2	ENSOGAP00000021888	ENSOGAP00000020128	Small ubiquitin-related modifier.	RAN binding protein 2.	0.994
H0Y0J5_OTOGA	RANGAP1	ENSOGAP00000021888	ENSOGAP00000007913	Small ubiquitin-related modifier.	Ran GTPase activating protein 1.	0.987
H0Y0J5_OTOGA	SAE1	ENSOGAP00000021888	ENSOGAP00000021461	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.987
H0Y0J5_OTOGA	SUMO3	ENSOGAP00000021888	ENSOGAP00000004215	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.823
H0Y0J5_OTOGA	UBA2	ENSOGAP00000021888	ENSOGAP00000007933	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.985
H0Y0J5_OTOGA	UBE2I	ENSOGAP00000021888	ENSOGAP00000001269	Small ubiquitin-related modifier.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.999
H0Y0J5_OTOGA	ZNF451	ENSOGAP00000021888	ENSOGAP00000000607	Small ubiquitin-related modifier.	Zinc finger protein 451.	0.540
PIAS1	H0XQT3_OTOGA	ENSOGAP00000012663	ENSOGAP00000018475	Protein inhibitor of activated STAT 1.	Small ubiquitin-related modifier.	0.911
PIAS1	H0Y0J5_OTOGA	ENSOGAP00000012663	ENSOGAP00000021888	Protein inhibitor of activated STAT 1.	Small ubiquitin-related modifier.	0.953