Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (625 aa)    
Predicted Functional Partners:
PRL
Growth hormone A1.
    
 0.998
JAK2
Tyrosine-protein kinase.
    
 0.995
STAT5B
Signal transducer and activator of transcription.
    
 0.981
JAK3
Tyrosine-protein kinase.
    
 0.975
KANK1
KN motif and ankyrin repeat domains 1.
   
    0.974
JAK1
Tyrosine-protein kinase.
    
 0.955
STAT5A
Signal transducer and activator of transcription.
    
  0.954
STAT6
Signal transducer and activator of transcription.
    
 0.954
LEPR
Leptin receptor.
     
 0.946
TYK2
Tyrosine-protein kinase.
    
 0.944
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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