Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM117BFamily with sequence similarity 117 member B. (486 aa)    
Predicted Functional Partners:
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
 
 0.966
DYNLL1
Dynein light chain.
    
   0.931
DYNLL2
Dynein light chain.
    
   0.928
TSC22D2
TSC22 domain family member 2.
    
 
 0.915
DCAF7
DDB1 and CUL4 associated factor 7.
    
 
 0.911
KEAP1
Kelch like ECH associated protein 1.
    
 
 0.890
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
    
 
 0.847
AMER1
APC membrane recruitment protein 1.
      
 0.763
KLHL17
Kelch like family member 17.
    
 
 0.758
TSC22D3
Uncharacterized protein.
    
 
 0.741
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: high (86%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.