Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ETV3LETS variant 3 like. (361 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase 3 beta.
    
  0.765
GSK3A
Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.
    
  0.765
SRF
Serum response factor.
    
 0.716
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
  0.638
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
  0.638
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
  0.638
LRRC71
Leucine rich repeat containing 71.
      
 0.595
DDX20
DEAD-box helicase 20.
    
 
 0.593
ETV6
ETS variant 6.
    
 0.533
RUNX2
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.503
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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