ERCC6 protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ERCC6

ERCC excision repair 6, chromatin remodeling factor. (1486 aa)

Predicted Functional Partners:

ERCC8

0.997

XPA

0.985

POLR2A

0.981

POLR2I

0.981

POLR2D

0.971

DDB1

0.968

POLR2B

0.966

TCEA1

0.965

BIVM

0.963

H0XGV5_OTOGA

0.963

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIVM	DDB1	ENSOGAP00000015320	ENSOGAP00000014421	Uncharacterized protein.	Damage specific DNA binding protein 1.	0.777
BIVM	ERCC6	ENSOGAP00000015320	ENSOGAP00000001396	Uncharacterized protein.	ERCC excision repair 6, chromatin remodeling factor.	0.963
BIVM	ERCC8	ENSOGAP00000015320	ENSOGAP00000018423	Uncharacterized protein.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.556
BIVM	H0XGV5_OTOGA	ENSOGAP00000015320	ENSOGAP00000015324	Uncharacterized protein.	XPGN domain-containing protein.	0.469
BIVM	POLR2A	ENSOGAP00000015320	ENSOGAP00000020302	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.815
BIVM	TCEA1	ENSOGAP00000015320	ENSOGAP00000019388	Uncharacterized protein.	Transcription elongation factor A1.	0.679
BIVM	XPA	ENSOGAP00000015320	ENSOGAP00000012444	Uncharacterized protein.	XPA, DNA damage recognition and repair factor.	0.958
DDB1	BIVM	ENSOGAP00000014421	ENSOGAP00000015320	Damage specific DNA binding protein 1.	Uncharacterized protein.	0.777
DDB1	ERCC6	ENSOGAP00000014421	ENSOGAP00000001396	Damage specific DNA binding protein 1.	ERCC excision repair 6, chromatin remodeling factor.	0.968
DDB1	ERCC8	ENSOGAP00000014421	ENSOGAP00000018423	Damage specific DNA binding protein 1.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.999
DDB1	H0XGV5_OTOGA	ENSOGAP00000014421	ENSOGAP00000015324	Damage specific DNA binding protein 1.	XPGN domain-containing protein.	0.777
DDB1	POLR2A	ENSOGAP00000014421	ENSOGAP00000020302	Damage specific DNA binding protein 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.744
DDB1	POLR2B	ENSOGAP00000014421	ENSOGAP00000014331	Damage specific DNA binding protein 1.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.709
DDB1	POLR2D	ENSOGAP00000014421	ENSOGAP00000015332	Damage specific DNA binding protein 1.	RNA polymerase II subunit D.	0.908
DDB1	POLR2I	ENSOGAP00000014421	ENSOGAP00000020582	Damage specific DNA binding protein 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.919
DDB1	TCEA1	ENSOGAP00000014421	ENSOGAP00000019388	Damage specific DNA binding protein 1.	Transcription elongation factor A1.	0.681
DDB1	XPA	ENSOGAP00000014421	ENSOGAP00000012444	Damage specific DNA binding protein 1.	XPA, DNA damage recognition and repair factor.	0.970
ERCC6	BIVM	ENSOGAP00000001396	ENSOGAP00000015320	ERCC excision repair 6, chromatin remodeling factor.	Uncharacterized protein.	0.963
ERCC6	DDB1	ENSOGAP00000001396	ENSOGAP00000014421	ERCC excision repair 6, chromatin remodeling factor.	Damage specific DNA binding protein 1.	0.968
ERCC6	ERCC8	ENSOGAP00000001396	ENSOGAP00000018423	ERCC excision repair 6, chromatin remodeling factor.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.997