Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRG4Proteoglycan 4. (1180 aa)    
Predicted Functional Partners:
LOC100946771
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
  0.696
LOC100956330
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
  0.696
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
     
  0.696
PLA2G4A
Phospholipase A2.
     
 0.628
LRG1
Leucine rich alpha-2-glycoprotein 1.
   
 
 0.619
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
      
 0.612
PDZD9
PDZ domain containing 9.
      
 0.587
FGFR1OP2
FGFR1 oncogene partner 2.
      
 0.553
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.548
ACAN
Aggrecan.
    
 
 0.547
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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