Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP4Insulin like growth factor binding protein 4. (258 aa)    
Predicted Functional Partners:
IGF1
Insulin like growth factor 1.
   
 0.995
IGF2
Insulin-like growth factor II (Predicted).
    
 0.993
IGFBP1
Insulin like growth factor binding protein 1.
    
 
 0.902
PAPPA
Pappalysin 1.
     
 0.821
IGFBP3
Insulin like growth factor binding protein 3.
   
 
 0.742
PAPPA2
Pappalysin 2.
     
 0.626
H0XBV9_OTOGA
C-type lectin domain-containing protein.
      
 0.578
FBLN2
Fibulin 2.
      
 0.562
FAM20C
FAM20C golgi associated secretory pathway kinase.
     
  0.469
IGFALS
Insulin like growth factor binding protein acid labile subunit.
      
 0.467
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.