Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNS4Tensin 4. (716 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.966
CBL
Cbl proto-oncogene.
    
   0.767
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.766
PPP3CA
Serine/threonine-protein phosphatase.
    
   0.755
ITGB2
Integrin beta.
    
 0.690
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
    
 0.690
KIF3B
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.673
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.622
H0XE40_OTOGA
Integrin beta; Belongs to the integrin beta chain family.
    
 0.622
ITGB4
Integrin beta.
   
 0.621
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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