Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (881 aa)    
Predicted Functional Partners:
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
    
 0.935
DDAH2
Dimethylarginine dimethylaminohydrolase 2.
    
   0.921
EPB41L2
Erythrocyte membrane protein band 4.1 like 2.
    
  0.917
EPB41L3
Erythrocyte membrane protein band 4.1 like 3.
    
  0.898
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
    
 
 0.888
EPB41
Erythrocyte membrane protein band 4.1.
    
  0.875
CNBD2
Cyclic nucleotide binding domain containing 2.
      
 0.815
C2CD5
C2 calcium dependent domain containing 5.
      
 0.717
EIF3A
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]
    
   0.706
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.702
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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