Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)    
Predicted Functional Partners:
MYCBP2
MYC binding protein 2.
    
 0.975
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
 0.948
MAP3K13
Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
     
  0.867
CASP9
Caspase 9; Belongs to the peptidase C14A family.
     
 0.787
FRA10AC1
FRA10A associated CGG repeat 1.
    
   0.767
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.681
MBIP
MAP3K12 binding inhibitory protein 1.
    
 
 0.656
TARS1
Threonyl-tRNA synthetase.
      
 0.590
DLK1
Delta like non-canonical Notch ligand 1.
      
 0.562
TARS2
Threonyl-tRNA synthetase 2, mitochondrial.
      
 0.549
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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