Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D15TBC1 domain family member 15. (691 aa)    
Predicted Functional Partners:
TBC1D17
TBC1 domain family member 17.
    
 0.990
NABP1
Nucleic acid binding protein 1.
   
    0.974
FIS1
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
    
 0.966
CLDN15
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
    
 0.946
RAB7A
RAB7A, member RAS oncogene family.
    
 0.931
OPTN
Optineurin.
   
 0.927
RAB7B
RAB7B, member RAS oncogene family.
   
 0.904
H0XAE3_OTOGA
DUF4515 domain-containing protein.
    
   0.893
ARMC5
Armadillo repeat containing 5.
   
 0.808
TBC1D5
TBC1 domain family member 5.
      
 0.768
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (16%) [HD]