Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)    
Predicted Functional Partners:
ASAH2
Neutral ceramidase.
    
 0.962
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
     
 0.946
CERK
Ceramide kinase.
    
 0.940
CERS3
Ceramide synthase 3.
    
 0.937
CERS2
Ceramide synthase 2.
    
 0.937
SMPD2
Sphingomyelin phosphodiesterase 2.
    
 0.932
SPHK2
Sphingosine kinase 2.
    
 0.928
CERS6
Ceramide synthase 6.
    
 0.928
SPHK1
Sphingosine kinase 1.
    
 0.928
CERS4
Ceramide synthase 4.
    
 0.924
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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