Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC20Cell division cycle 20. (500 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.999
BUB1B
Uncharacterized protein.
   
 0.999
BUB3
BUB3 mitotic checkpoint protein.
   
 0.999
CDC27
Cell division cycle 27.
   
 0.999
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.999
NEK2
NIMA related kinase 2.
   
 0.998
ANAPC5
Anaphase promoting complex subunit 5.
    
 0.998
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
   
 0.998
CDC23
Cell division cycle 23.
   
 0.998
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.