Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (139 aa)    
Predicted Functional Partners:
GSTK1
Glutathione S-transferase kappa.
    
 0.965
GSTM3
Glutathione S-transferase.
   
 
 0.943
PRDX6
Peroxiredoxin 6.
  
 0.941
H0XEL2_OTOGA
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 0.941
H0XNT6_OTOGA
Uncharacterized protein.
   
 0.941
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.940
PPARGC1A
PPARG coactivator 1 alpha.
     
 0.933
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.930
H0WJI5_OTOGA
Uncharacterized protein; Belongs to the GST superfamily.
   
 
 0.920
MGST1
Microsomal glutathione S-transferase 1.
   
 
 0.911
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (22%) [HD]